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It may make us uncomfortable, but there are ethical reasons to use animals in medical research
It may make us uncomfortable, but there are ethical reasons to use animals in medical research
The media regularly report impressive medical advances. However, in most cases, there is a reluctance by scientists, the universities or research institutions they work for, and the media to mention animals used in that research, let alone non-human pr...
Scientists identify potential marker of EoE disease activity
Scientists identify potential marker of EoE disease activity
A potential marker of disease activity for a severe and often painful food allergic disease called eosinophilic esophagitis (EoE) has been discovered by researchers, possibly sparing children with EoE the discomfort and risk of endoscopic procedures to...
Research brings new hope for pediatric brain tumors
Research brings new hope for pediatric brain tumors
Childhood brain tumors are the second-most frequent malignancy of childhood and the most common form of solid tumor. A lack of treatment options keeps survival rates low. Unlike adults with brain cancer, children cannot receive radiation therapy, so ph...
Researchers: Pancreatic cancer is '4 separate diseases'
Researchers: Pancreatic cancer is '4 separate diseases'
After carrying out a detailed analysis of DNA disruption, gene expression and molecular pathways in hundreds of tumors, researchers conclude pancreatic cancer is not one but four separate diseases, each with a different genetic trigger and requiring a ...
Understanding diversity within the clinical laboratory profession
Understanding diversity within the clinical laboratory profession
The Affordable Health Care for America Act is providing increased access, opening doors to a global economy and further changing the demographics and dynamics of healthcare, making diversity a necessity.
CDC: Obesity prevalence tops 30 percent in US population
CDC: Obesity prevalence tops 30 percent in US population
The prevalence of obesity among adults in the U.S. passed 30 percent for this first time ever last year, according to new numbers from the Centers for Disease Control and Prevention.
Sepsis: New definition may help cut risks of deadly infection
Sepsis: New definition may help cut risks of deadly infection
An international task force has come up with a new definition of sepsis that could cut the infection risk.
Laboratory nitrogen generators: Why not do it yourself?
Laboratory nitrogen generators: Why not do it yourself?
Where does your lab get its nitrogen? For decades, most groups had nitrogen cylinders trucked in, sometimes from great distances. The gas in those cylinders was most likely generated using fractional distillation of air, a large-scale, energy-hogging i...
Inside the top-secret drone laboratory where life-saving technologies are made
Inside the top-secret drone laboratory where life-saving technologies are made
The Zipline International headquarters sit on a patch of farmland that clings to the California coast.
Medical labs may be killing horseshoe crabs
Medical labs may be killing horseshoe crabs
The biomedical industry harvests hundreds of thousands of horseshoe crabs each year because their rich blue blood contains a protein that thickens when it comes in contact with impurities. The crabs are bled for this substance, known as limulus amebocy...
FDA clears genetically engineered mini pig model for use in research and drug development
FDA clears genetically engineered mini pig model for use in research and drug development
Exemplar Genetics announced that the U.S. Food & Drug Administration has cleared its low-density lipoprotein receptor mini pig for use in scientific studies. In the future, this type of model could become an invaluable addition to study diseases such a...
New study indicates shopping tools alone might not lower medical spending, even though more patie...
New study indicates shopping tools alone might not lower medical spending, even though more patie...
Can shopping tools designed to help patients compare providers (including medical laboratories), quality, and prices, make a contribution to reducing the increase in healthcare costs? A new study suggests that such shopping tools make only modest contr...
Managing energy in your lab
Managing energy in your lab
According to the U.S. Department of Energy's Office of Energy Efficiency & Renewable Energy, U.S. laboratories use much more water and energy per square foot than other facilities and office buildings. That higher energy use is due to labs' stricter he...
Google files patent for needle-free blood draw system that could eventually remove clinical labs,...
Google files patent for needle-free blood draw system that could eventually remove clinical labs,...
Google, (now known as Alphabet Inc.) recently filed an application for another patent that deals with medical laboratory test technology. This patent application is for a needle-free blood draw system that enables patients to perform diagnostic testing...
Two thirds of clinical trials unpublished 2 years later
Two thirds of clinical trials unpublished 2 years later
Leading academic research centers are doing a poor and variable job of disseminating clinical trial results, according to a cross-sectional analysis published online recently in BMJ, and that is leading to serious information gaps and ethical lapses.
Raman spectroscopy: New approaches for clinical diagnostics
Raman spectroscopy: New approaches for clinical diagnostics
When light hits a molecule, it vibrates and the scattered light creates a fingerprint of that molecule. This Raman spectroscopy opens new approaches in clinical diagnostics for many medical conditions. "It's a biochemically specific technique that is s...
'Liquid' cancer test offers hope for alternative to painful biopsies
'Liquid' cancer test offers hope for alternative to painful biopsies
A blood test to detect cancer mutations produced results that generally agree with those of an invasive tumor biopsy, researchers reported, heralding a time when diagnosing cancer and monitoring its progression may become less painful and risky.
White House finishes review of Medicare pay rule for labs
White House finishes review of Medicare pay rule for labs
Medicare payments for clinical lab tests are poised for an update under a long-delayed final rule that the White House cleared June 15.
Antibody discovery shows promise for developing HIV vaccine
Antibody discovery shows promise for developing HIV vaccine
Scientists at the National Institutes of Health have made what could be a groundbreaking finding in the fight against HIV. While observing the immune response of an HIV-infected patient, researchers discovered a new antibody that targets a weak spot in...
Ebola survivor study yields insights on complications of disease
Ebola survivor study yields insights on complications of disease
Preliminary findings from PREVAIL III, a study of Ebola virus disease survivors being conducted in Liberia, indicate that both Ebola survivors and their close contacts have a high burden of illness. However, the prevalence of eye, musculoskeletal and n...
Concierge medicine increases in popularity as more consumers opt for this model; will clinical la...
Concierge medicine increases in popularity as more consumers opt for this model; will clinical la...
One big challenge for clinical laboratories and anatomic pathology groups is how to adapt to the changing role of the consumer in healthcare. It a major goal of healthcare policymakers to have patients pay more out of pocket for clinical care so as to ...
Pathology software startup using data analytics to aid cancer diagnosis has raised $1 million
Pathology software startup using data analytics to aid cancer diagnosis has raised $1 million
Proscia, a health IT startup that developed a platform for digital pathology software aimed at clinicians and researchers to make the process of sharing and storing data easier to support cancer diagnoses and treatment has raised $1 million in a Seed r...
The future of data and technology in clinical trials
The future of data and technology in clinical trials
In advance of its upcoming Data & Technology in Clinical Trials 2016 conference, eyeforpharma has released a report on the future of data and technology adoption in clinical trials. "An Industry View Point: The Future of Leveraging Data & Technology in...
Nanogel that delivers one-two punch to cancer heads to clinical trial
Nanogel that delivers one-two punch to cancer heads to clinical trial
An immunotherapy drug delivery system created at Yale that can carry multiple drugs inside a tiny particle is heading toward its first phase of clinical trials for a possible new treatment for cancer.
Neuroimaging helps distinguish abnormalities in the brains of NFL players
Neuroimaging helps distinguish abnormalities in the brains of NFL players
Perfusion neuroimaging using SPECT can detect abnormalities in the brains of retired and current National Football League players, distinguishing them from healthy control subjects, according to results of a new study published online in the Journal o...
Researchers one step closer to understanding regeneration in mammals
Researchers one step closer to understanding regeneration in mammals
A long-standing question in biology is why humans have poor regenerative ability compared to other vertebrates? While tissue injury normally causes us to produce scar tissue, why can't we regenerate an entire digit or piece of skin? A group of Universi...
Expecting data from Theranos, lab experts get new product
Expecting data from Theranos, lab experts get new product
It was expected to be an academic presentation to show if Theranos Inc.'s controversial blood-testing technology worked, and perhaps explain the science behind the claims that the startup could do lab tests with a fraction of the blood and cost of trad...
Injectable nanoparticles show 'astounding' prowess against cancer
Injectable nanoparticles show 'astounding' prowess against cancer
Nanotechnology is being heralded by many researchers as the future of medical science. A new study published recently in Nature Biotechnology provides an incredible insight into this brave, new, miniaturized future.
Insulin-producing cells grown in lab control glucose spikes in diabetic mice
Insulin-producing cells grown in lab control glucose spikes in diabetic mice
A long-standing obstacle in developing a cell therapy for diabetes has been getting beta cells derived from human stem cells to mature beyond the precursor stage into fully-functioning insulin releasers.
Could space research offer new hope for cancer patients?
Could space research offer new hope for cancer patients?
The nano age and space age have converged in a partnership that could usher in a new era of hope for cancer patients.
Discarded drug helps fight disease-causing viruses in lab
Discarded drug helps fight disease-causing viruses in lab
Researchers found a drug discarded by the company GlaxoSmithKline because of side effects during clinical trials helped human cells fight off two viruses, according to a new study.
Steady increase in number of workers with 'critical illness' coverage presents clinical labs and ...
Steady increase in number of workers with 'critical illness' coverage presents clinical labs and ...
Policies with this lump-sum payment feature are sometimes referred to as critical illness coverage. Such policies typically pay a lump sum if someone is diagnosed with cancer, suffers a heart attack, stroke, kidney failure, or needs an organ transplant...
Study: Mentoring programs needed to boost interest in research careers
Study: Mentoring programs needed to boost interest in research careers
Clinician-scientists are a rare breed — they wear two very important hats, which help bridge the gap between basic and clinical science.
Aggressive breast cancer identified with new technique
Aggressive breast cancer identified with new technique
Currently, when a woman is diagnosed with the earliest stage of breast cancer - called ductal carcinoma in situ - there is no way of knowing if it is going to be aggressive or not.
Molecular testing labs: At forefront of precision medicine
Molecular testing labs: At forefront of precision medicine
The days of one-size-fits-all medicine are numbered. Instead of assuming everyone with the same condition needs the same medications and the same dosages, care providers are transitioning to "precision medicine," where medications, dosages and even exe...
CDC investigating 14 new potential cases of sexually transmitted Zika
CDC investigating 14 new potential cases of sexually transmitted Zika
The Centers for Disease Control and Prevention said recently that it is investigating 14 new reports of potential sexual transmission of the Zika virus in the United States. Several of the cases involve pregnant women. In at least two of the cases, a Z...
Study highlights need for better characterized genomes for clinical sequencing
Study highlights need for better characterized genomes for clinical sequencing
A new study that assesses the accuracy of modern human-genome-sequencing technologies found that some medically significant portions of an individual's DNA blueprint are situated in complex, hard-to-analyze regions that are currently prone to systemati...
Excessive tests don't benefit patient, do increase cost in age-related immune disorder
Excessive tests don't benefit patient, do increase cost in age-related immune disorder
A series of tests physicians routinely order to help diagnose and follow their patients with an elevated antibody level that is a marker for cancer risk, often do not benefit the patient but do increase health care costs, pathologists report.
Trading in medical data: Headache or an opportunity for pathologists and clinical labs
Trading in medical data: Headache or an opportunity for pathologists and clinical labs
When it comes to patient privacy, pathologists and clinical laboratory managers may be spending more time addressing a growing issue with the patient data their labs create and store. Third-party data brokers want to position themselves to collect heal...
Bladder cancer type bears molecular features of breast cancer
Bladder cancer type bears molecular features of breast cancer
The unraveling of the human genome has triggered a shift toward classifying cancer according to patterns found in molecules and genes rather than cells and tissues. An example of this trend is a new study that defines a new subtype of bladder cancer th...
Are popular at-home genetic kits misleading?
Are popular at-home genetic kits misleading?
Relatively inexpensive genetic test kits, such as 23andMe and Pathway Genomics, are becoming popular. But choosing an at-home kit over a laboratory test could lead to potentially risky consequences, a new paper warns. Researchers at the National Instit...
Protein that could prevent tumor growth in cervical cancer identified
Protein that could prevent tumor growth in cervical cancer identified
UCLA scientists have identified a protein that has the potential to prevent the growth of cervical cancer cells. The discovery could lead to the development of new treatments for the deadly disease.
Green tea compound shows promise for treating rheumatoid arthritis
Green tea compound shows promise for treating rheumatoid arthritis
A compound found in green tea could be an effective treatment for rheumatoid arthritis, according to the results of a new study.
A better 3-D camera with clear, graphene light detectors
A better 3-D camera with clear, graphene light detectors
A camera that can record 3-D images and video is under development at the University of Michigan, with $1.2 million in funding from the W.M. Keck Foundation.
Xanthohumol in lab tests lowers cholesterol, blood sugar and weight gain
Xanthohumol in lab tests lowers cholesterol, blood sugar and weight gain
A recent study at Oregon State University has identified specific intake levels of xanthohumol, a natural flavonoid found in hops, that significantly improved some of the underlying markers of metabolic syndrome in laboratory animals and also reduced w...
How a pill could improve breast cancer diagnoses
How a pill could improve breast cancer diagnoses
The ongoing debate about breast cancer diagnostics has left many women confused — particularly over what age they should get mammograms and who needs treatment. An issue with current methods is that they often identify lumps but cannot conclusive...
Mitochondrial dynamics impair nervous system development in Wolfram syndrome
Mitochondrial dynamics impair nervous system development in Wolfram syndrome
Although mitochondria, the tiny capsules that produce energy for the cell, are known to play some role in neurodevelopmental and psychiatric disorders, the contribution of mitochondrial dynamics (mitochondrial trafficking, the regulated fusion and fiss...
The lab and terrorism
The lab and terrorism
San Bernardino. Brussels. Paris. Recent terrorist acts have reminded laboratory managers, as well as entire hospital staffs, that systemwide preparedness is imperative. Mandates from the American College of Pathologists, the Joint Commission and Det No...
Dogs test drug aimed at humans' biggest killer: Age
Dogs test drug aimed at humans' biggest killer: Age
Ever since last summer, when Lynn Gemmell's dog, Bela, was inducted into the trial of a drug that has been shown to significantly lengthen the lives of laboratory mice, she has been the object of intense scrutiny among dog park regulars.
Researchers use mouse model to study craniofacial disorders
Researchers use mouse model to study craniofacial disorders
Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the ...
Nanograft seeded with 3 cell types promotes blood vessel formation to speed wound healing
Nanograft seeded with 3 cell types promotes blood vessel formation to speed wound healing
Large or slow-healing wounds that do not receive adequate blood flow could benefit from a novel approach that combines a nanoscale graft onto which three different cell types are layered. Proper cell alignment on the nanograft allows for the formation ...
The case for digital pathology
The case for digital pathology
Pathology plays a critical role in the detection of disease, particularly cancer. At times, patients and their families wait weeks to learn of their ultimate diagnosis, which is contributed to, in part, by the current conventional processes. The road t...
Theranos startup chief banned from medical labs
Theranos startup chief banned from medical labs
Elizabeth Holmes, founder and CEO of the blood-testing startup Theranos, has been banned by the government from owning or running a medical laboratory for two years, according to a company statement.
Nearly one-third of traditional medicare payments now based on value-based reimbursement and alte...
Nearly one-third of traditional medicare payments now based on value-based reimbursement and alte...
Clinical laboratory executives should take note of a key financial fact. The transition from fee-for-service healthcare to value-based reimbursement is occurring at a faster clip than the Department of Health and Human Services anticipated last year wh...
Researchers investigate four promising new treatments for Lyme disease
Researchers investigate four promising new treatments for Lyme disease
The ticks that transmit Lyme disease have multiplied aggressively over the past 20 years and now thrive in half of all counties in the U.S., according to a recent study in the Journal of Medical Entomology.
Exposure to routine viruses makes mice better test subjects
Exposure to routine viruses makes mice better test subjects
Vaccines and therapeutics developed using mice sometimes don't work as expected in humans. New research points to the near-sterile surroundings of laboratory mice as a key reason. When the researchers infected laboratory mice with the mouse equivalent ...
Virtual reality lets med students experience what it's like to be 74
Virtual reality lets med students experience what it's like to be 74
Elder care is about to become much more empathetic. Embodied Labs has come up with a new virtual reality program called "We Are Alfred," which allows young medical students to feel what it's like to be an elderly individual experiencing audio and visu...
Duke researchers develop 'swarmbot' strain that lowers risk of contamination in bacteria research
Duke researchers develop 'swarmbot' strain that lowers risk of contamination in bacteria research
Duke researchers have engineered bacteria that cannot survive outside their colony, lowering the risk of contamination that normally accompanies genetically engineered microorganisms.
IBM lab-on-a-chip breakthrough aims to help physicians detect cancer
IBM lab-on-a-chip breakthrough aims to help physicians detect cancer
IBM scientists have developed a new lab-on-a-chip technology that can, for the first time, separate biological particles at the nanoscale and could enable physicians to detect diseases such as cancer before symptoms appear.
What's the key to halting healthcare hacking?
What's the key to halting healthcare hacking?
Healthcare records for 1 in 3 Americans were breached in 2015, with records of nearly 112 million people affected by hackers, compared with only about 1.8 million individuals in 2014. That's the finding of cybersecurity vendor Bitglass, following the a...
Skin with hair follicles and glands grown in lab
Skin with hair follicles and glands grown in lab
Tissue engineering of skin has come a long way in recent years, but it is struggling to progress from growing simple 2-D sheets of tissue cells to regenerating a functioning, complex 3-D organ complete with hair follicles, glands and connections to oth...
How scientists plan to 'grow' drones of the future in a lab
How scientists plan to 'grow' drones of the future in a lab
It takes years to build a drone using conventional manufacturing techniques. From the initial mining of materials to the maiden flight is a long, complicated path with countless industrial processes involved.
New snakebite treatment under development at UA
New snakebite treatment under development at UA
Time is of the essence for treating venomous snakebites and a product being developed by researchers at the University of Arizona College of Medicine–Tucson may extend that window for treatment. The researchers hope this new treatment will delay ...